Golden Ginkgo Biloba
Herbal Health Supplement
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Suggested
Retail Price:$19.95
Your Price:$14.96

The World's Oldest Living Tree?
The history of this wonderful herb is a
living symbol of "Life Extension" and
"Cognitive Enhancement". Ginkgo biloba
is literally a living fossil that has survived
virtually unchanged through the various
ice ages of prehistory. Some scientists
estimate that it is 200 million years old,
the oldest living tree species on the earth.1
Ginkgo has been transplanted all over the
world and continues to thrive even under
adverse conditions, demonstrating its
apparent immunity to pollution, insects
and disease. Ginkgo even survived the
atomic bombing of Hiroshima, where it
still grows today next to the epicenter of
the explosion. Individual trees may live
to as many as 2000 years or more.
Ginkgo has been a mainstay of traditional
Chinese medicine for more than 5000
years. Perhaps the ancient Taoist Monks
had some vision of the future of Ginkgo
as a brain and memory tonic when they
planted it ceremonially in places of honor
in their monasteries. They felt that this
two lobed, fan-shaped leaf (biloba) represented
the two phases of Yin and Yang
in Taoist Philosophy. Ginkgo was planted
to portray wisdom, centeredness and a
meditative state.
A Natural
Phytochemical Wonder
More than one thousand scientific papers
have been published worldwide to
document the clinical effects of Ginkgo
biloba extract and to explain its varied
mechanisms of action. The scientific community
now believes that the clinical benefits
of this ancient herb result from a
group of bioflavonoids called Ginkgoflavonglycosides and from a group of
lactone terpenes called Ginkoglides
which include Ginkgolide A, Ginkgolide
B, Ginkgolide C and Bilobalide.
It takes anywhere from 50 to 75 pounds
of leaves to make one pound of the concentrated
Ginkgo biloba extract (GBX).
As a measure of potency, researchers
have established a common standard
content of 24% ginkogosides and 6%
terpenes.2
This standardization process during
manufacturing is critical to the effectiveness
of the end product. By using a standardized
product, one is assured that
they are receiving this "Natural Cocktail"
of phytochemical constituents, not
just some ground up leaves that may, in
fact, contain little, if any, of these efficacious
agents.
Ginkgo Secrets
Ginkgo has been used preponderantly
in Chinese Medicine for over 5,000 years
to treat age-related circulation disorders,
memory loss, cancer, asthma and other
pulmonary diseases, impaired hearing
and sexual dysfunctions, just to name a
few. However, its enormous popularity
did not come about until it
was rediscovered by Western
medicine some 40 years
ago. Since that time, Ginkgo
has become one of the most
frequently prescribed medicines
in Germany and
France. Its popularity in the
United States is nothing
short of phenomenal, fueled
by its demonstrable clinical
benefits, rather than by the
"hype" that has popularized
so many herbs.
Ginkgo Biloba's
Notable Benefits:
Brain Function: In order for the brain to
function properly, it needs to be bathed
in a constant supply of oxygen and nutrient
rich blood. Any malfunction that interrupts
the blood flow can have a profound
effect on mental function. If allowed
to occur chronically over many
years due to atherosclerosis, the result is
often the familiar loss of cognitive function
and dementia, including memory
lapses, loss of concentration, decreased
intellectual ability, impaired vision, anxiety,
loss of equilibrium and dizziness.
Impaired blood flow can also be an underlying
factor of headaches, depression,
confusion and , in the most severe cases,
stroke.
The special bioflavonoids in Ginkgo have
a stronger biological activity than most
other bioflavonoids and seem to have a
specific affinity for the capillary beds of
the brain..3 Their function includes:
Dilation of blood vessels resulting in improved
flow of blood to and from tissues
all over the body, especially the brain.4
Increasing the oxygen content of the
blood. It has been shown that oxygenrich
blood enhances the memory.5
Improved cellular transmission. All neural
functions of the brain are achieved by
neural transmitters. These are the chemicals
that allow one neural unit to communicate
with another. The better the neural
transmission, the more effectively
memory and other brain functions work.
Ginkgo biloba both increases the amount
of neural transmission and increases the
number of receptor sites for neural transmission.
6 Again, this dramatically improves
brain function.
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| By using a standardized product, one
is assured that they are receiving this
"Natural Cocktail" of phytochemical
constituents, not just some ground up
leaves that may, in fact, contain little,
if any, of these efficacious agents.
Dr. Larry J. Milam H.M.D. |
Improved cognitive function. 7 In a random,
double blind, placebo controlled
German study conducted in the mid
1980s, 40 people (aged 60-80 years) diagnosed
with slight to moderate dementia
received either Ginkgo biloba extract or a
placebo for three months. By week four,
the group taking Ginkgo biloba extract
was performing significantly better than
the placebo control on standard clinical
geriatric tests. They also showed marked
improvement in their mental capacity,
alertness, sociability and mood and continued
to improve as the study progressed.
The placebo group did not
change at all over the 12 weeks of the
study (see Figure 1).

Inhibiting Platelet Activating Factor
(PAF) A common trend in heart disease,
strokes and peripheral vascular disease
(e.g., intermittent claudication or painful
walking), is the formation of blood clots
(thrombosis) within the circulatory system.
Underlying these clots is an excess
of platelet activating factors (PAFs), which
induce platelet aggregation, neutrophil
degranulation and oxygen free radical production.
As a result, excess PAFs are at least partly
responsible for thrombosis,
bronchoconstriction (as occurs in
asthma), shock reaction (cardiogenic and
anaphylactic) and organ transplant rejection.
PAFs can be stimulated by chronic
stress, a diet high in processed hydrogenated
fats and exposure to allergens. Numerous
studies have confirmed that
Ginkgo biloba extract is an extremely effective
agent for inhibiting PAFs
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| Treatment with
Ginkgo biloba
extract has been
shown to result in
improved cerebral
metabolism and a
reduced risk of
hypoxic damage
to the brain |
Blocking Asthma Attacks. Inhibiting
PAFs with Ginkgo biloba extract may help
some patients with asthma. Some studies
have shown that PAFs play an important
role in causing airway inflammation.
Chinese physicians have known about
the beneficial effects of Ginkgo biloba for
asthma patients for thousands of years.
In a preliminary trial conducted in Belgium,
six out of ten children with severe
asthma were found to improve "dramatically"
within the first three to four days
of taking Ginkgo biloba extract. Three
other children improved "very substantially",
but still occasionally required
other therapy.9
Improved cerebral
metabolism
Treatments with Ginkgo
biloba extract have been
shown to result in improved
cerebral metabo-lism and a reduced risk of hypoxic damage
to the brain.10 In a 12 week study, 24
patients hospitalized with a form of dementia
due to occluded cerebral arteries
were treated with Ginkgo biloba extract
(120 mg/day) or a placebo. The patients
treated with Ginkgo biloba extract were
found to improve significantly on all measurements,
including EEG finding, reaction
time and concentration. Using the
venous micro-embolic index (VMI), a
measurement of platelet aggregation, the
researchers found that platelet
aggregration declined progressively in
the treated patients from a high of 3.6 at
baseline to 1.3 at week 12. There was no
change in the VMI of the placebo group
(see Figure 2).
Fighting Free Radicals Bioflavonoids
have long been considered great antioxidants,
specifically for protecting the microcirculation
in small blood vessels.
Ginkgo is an extraordinary free radical
scavenger that is particularly effective
against the superoxide anion (-02), a dangerous
free radical that has been directly
or indirectly implicated in cell damage.11
Numerous studies have demonstrated
that Ginkgo biloba extract is very effective
in blocking lipid peroxidation, thus
protecting cell membranes which are primarily
composed of lipids.12 This is extremely
important in brain cells which
contain a higher content of lipids than
any other cells in the body.
Beyond brain cell protection, other clinical
studies suggest a wide range of clinical
benefits beyond its life enhancing
antioxidants such as:
Radiation induced chromosomal damage
protection. Because of its powerful effect,
Ginkgo biloba extract was given to
Chernobyl recovery workers. After two
months, it was determined that it completely
protected them from further chromosomal
damage. |
Special Note:
While studies show Ginkgo biloba extract may be
effective in preventing some asthma attacks, it is probably
not effective for treating an acute attack. As
with any medical condition, one should consult with
a health care professional for immediate relief. |
Ischemia induced spinal cord injury protection.
Ischemia-induced lipid
peroxidation is one of the main factors that
produces tissue damage in spinal cord injury.
When Ginkgo biloba extract was
given to rats subjected to experimental
spinal cord injury, they were protected
from the paraplegic effects of the injury to
a significant degree.14
Heart muscle ischemia and reper-fusion
injury protection. Heart muscle
is extremely sensitive to the lack of oxygen
(ischemia) caused by heart attacks
and blood vessel restrictions or clots.
However, just as damaging is the sudden
rush of restoration oxygen which can carry
with it a rush of free-radicals, as occurs
following coronary bypass surgery.
Ginkgo biloba extract, because of its antioxidant
activity, has shown its ability to
protect heart tissue when exposed to
these insults 15 16 17
Protection against Retinal Damage. Damaged,
leaking or injured delicate retinal
cells is a common cause of blindness in
people with diabetes and other macular
problems. Numerous studies have shown
that Ginkgo biloba extract reduces the susceptibility
of these cells to injury .
Other Uses of Ginkgo biloba
Although Ginkgo biloba is known as one
of the most important herbs for the brain,
its action and benefits are not exclusively
for the brain.
• The ginkgosides it contains work as
an herbal antioxidant throughout the
entire body.
• The microcirculation of all capillary beds
throughout the body will be enhanced.
• Ginkgo can help all organs that have a
rich blood supply including the heart,
liver, kidneys, lungs and spleen.
• Ginkgo has been clinically shown to
provide appropriate benefit for such
conditions as ringing in the ear (tinnitus),
headaches, vertigo (dizziness),
hearing loss, depression, allergies, atherosclerosis,
cardiac arrhythmia, diabetic
peripheral vascular disease, eczema,
glaucoma, impotency, retinitis
and neuralgia, as well as the initial
stages of Alzheimer's disease.
How much
Ginkgo biloba
is beneficial?
Various studies have been conducted using
dosages from 30 mg to 600 mg per
day. However, in many studies, there is
no reference to the levels of the primary
actives such as ginkogosides and terpenes.
Obviously, a Standardized Formula
would be more effective at lower dosages.
For best results use only Ginkgo biloba
that has been standardized to contain a
content of 24% ginkgosides and 6% terpenes.
Non-standardized products may
not be effective.
As a dietary supplement to enhance brain
function and prevent circulatory disorders,
begin with a minimum of 60 mg. each
day, increasing your daily consumption
to 120 mg. For chronic long term conditions,
360 mg per day (6-60mg capsules
per day) is the dosage recommended by
most herbalists. It is recommended that
you take the least amount at which you
can see measurable results. Long term
studies indicate that there are no toxicity
concerns, even at levels of 600 mg. or
more.
Greater benefits may be obtained when
the product is enhanced with other natural
herbs such as Aloe Vera Extract.
Conclusion
Ginkgo biloba has been around since the
age of dinosaurs. It has survived mass
extinctions, ice ages, atomic explosions
and environmental pollutants without
damage. Visionary healers have tapped
the resources of this amazing herb since
the beginning of recorded history.
Now with the aid of advanced diagnostic
equipment and devices, we are able to
unlock some of the mysteries of its phytochemical
composition and release its
secrets to the masses. It may well be the
world's oldest "smart drug".
To ensure that you obtain the greatest
possible benefit, check the label and select
only standardized formulas from reputable
companies willing to produce a certificate
of analysis.
1 Ginkgo Biloba: The World's Oldest Anti-Aging
Secret, Life Enhancement News, Dec. 1996.
p.1
2 Willard, Terry, Ginkgo Biloba: Good for the
2.8 -
2.6 -
2.4 -
2.2 -
2.0 -
1.8 -
1.6 -
1.4 -
1.2 -
1.0 -
-4 -2 0 2 4 6 8 10 12
Weeks
Reduced Cerebral Blood Clotting Following
Treatment with Ginkgo biloba Extract
Placebo
n n
n
n n
Ginkgo biloba
¢ ¢ ¢ ¢
Figure 2. Decline in platelet aggregation in patients diagosed with cerebro-organic
syndrom, a form of dementia caused by atherosclerosis in cerebral arteries. (Source:
Hofferberth, 1991)
Ù
Ù
Mean reaction Time
Brain, and More, Vitamin Retailer, Nov. 1995.
p. 58.
3 Ibid. p. 59.
4 Ginkgo Biloba: The World's Oldest Anti-Aging
Secret, Life Enhancement News, Dec. 1996.
p.2.
5 Le Ponein-Lafitte, M., et al; Ischemie cerebral
apres ligature non stimultanc de arteres
carotide chez l rat: effect de l'extract of ginkgo
biloba on rabbit isolated aorta, Gen Phamac.,
13,225,1982.
6 Willard, Terry, Ginkgo Biloba: Good for the
Brain, and More, Vitamin Retailer, Nov. 1995.
p. 59.
7 Ginkgo Biloba: The World's Oldest Anti-Aging
Secret, Life Enhancement News, Dec. 1996.
p.4-5.
8 Ibid. p. 485
9 Ibid. p. 5-6.
10 Ibid. p. 5.
11 Princemail, J., Dupuis M., Nasr C.,et al. Superoxide
anion scavenging effect and superoxide
dismutate activity of Ginkgo biloba extract.
Experientia. 1989;45:708-712.
12 Ibid. p. 6.
13 Emerit I, Oganaesian N., Sarkisian T, et al.
Clastogenic factors in the plasma of Chernobyl
accident recovery workers: anticlastogenic effect
of Ginkgo biloba extract. Radiat Res.
1995;144: 198-205.
14 Koc RK., Akdemir H, Kurtsoy A, et al. Lipid
peroxidation in experimental spinal cord injury.
Comparison of treatment with Ginkgo
biloba, TRH, and methyprednisone. Res Exp
Med. 1995;195:117-123.
15 Shen JG, Zhou DY. Efficiency of Ginkgo biloba
extract (EGB 761) in antioxidant protection
against myocardial ischemia and reperfusion
injury. Biochem Mol Biol Int. 1995;35:125-134.
16 Tosaaki A, Engelman DT, Pali T, Engleman
RM, Droy-Lefaix MT. Ginkgo biloba extract
(EGb 761) improves postischemic function in
isolated preconditional working rat hearts.
Coron Artery Dis. 1994;35:125-134.
17 Haramaki N. Aggarwal S. Kawabata T. Droy-
Lefaix MT, Packer L. Effects of natural antioxidant
Ginkgo biloba extract (EGb 761) on
myocardial ischemia-reperfusion injury. Free
Radic Biol Med. 1994;16:789-794.
18 Ginkgo Biloba: The World's Oldest Anti-Aging
Secret, Life Enhancement News, Dec. 1996.
p.7.
19 Willard, Terry, Ginkgo Biloba: Good for the
Brain, and More, Vitamin Retailer, Nov. 1995. |
| The ideas, procedures and suggestions in this article are
intended to supplement, not replace, the medical advice of
trained professionals. In addition, all matters regarding
your health require medical supervision. Consult your
physician about any condition that may require diagnosis
or medical attention. |
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